Developing Peripheral Neuropathy after starting Methotrexate

Posted Fri 16 Nov 2018 22.49 by Richard S

I have PsA and started 15 mg methotrexate about three or four weeks ago. The last two nights, as I am falling asleep, I experienced a burning sensation in my feet and sometimes shooting nerve pain. I have PsA in my feet but this is very different. It can last through most of the night but gets better by the morning. I'm pretty sure its peripheral neuropathy which is a side-effect of MTX. Question. Other than stopping MTX, is there anything I can do to prevent this? Maybe take more folic acid? Just wondering if anyone has experienced this and what if anything can be done to help. I also read that in some cases, the neuropathy will eventually go away on its own. Any help would be greatly appreciated.

Posted Sat 17 Nov 2018 12.16 by OhNo_NotAgain? (edited Mon 19 Nov 2018 11.29 by OhNo_NotAgain?)

Your question would be a good one to ask the specialist that prescribed you the methotrexate and who is probably expecting to monitor your condition and your body's reaction to the treatment.

Posted Sun 25 Nov 2018 14.31 by Richard S

Hi Wendy, Thank you for your reply. I am glad to hear that you are doing better and the FODMAPS diet is helping. I have been trying different types of diets for the past two years and have not had a lot of success. I do however seem to do better when I avoid starches and grains. Even pseudo grains like quinoa bother me. I just ordered a book on FODMAPS and I am a little overwhelmed with what to do. I would very much appreciate to know what foods you are eating and what foods you are getting your main calories from. Sincerely, Richard

Posted Mon 26 Nov 2018 14.53 by Richard S

Wendy, Thank you so much for your reply! It has helped me to get motivated. Thanks for the app suggestion. I will try to find an app to download. I spent the last couple of days reading The Complete FODMAP Diet and feel more motivated. Thanks for taking the time to list out what you are eating:)

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