Take Part in Research

See below for opportunities to take part in psoriasis research, or to share your experiences. Please note that these projects are not run by the Psoriasis Association, but by external parties such as academic research departments.

We do not normally advertise commercial clinical trials. If the opportunities below do not match the type of project you are looking to be involved in, you can also take a look at 'Be Part of Research', which is run by the National Institute for Health Research (NIHR) and will give you lots of information about taking part in clinical trials and allow you to search for a relevant trial in your area. More information about clinical trials can also be found on the NHS website and at ClinicalTrials.gov.

PsOAR Study (Psoriasis of the Anogenital Region)

Researchers are currently organising focus groups to explore the experiences of patients with anogenital psoriasis.

Anogenital psoriasis (in comparison to other types of psoriasis which may be more visible) is not often talked about by patients and doctors, and we have less information and evidence on for example on the best treatments for this condition. We would like to gain insight from patients living with the condition via focus groups to help inform a future clinical trial looking at the best treatment options.

Recruitment criteria

  • Aged 18 or over
  • A diagnosis of anogenital psoriasis by a dermatology specialst
  • Willing to discuss your experiences via a small online focus group (3-5 people) lasting 1- 2 hours, held on Microsoft Teams (can be anonymous if preferable)
  • Research team contact email: psoar@nottingham.ac.uk

Understanding the experiences and opinions of people living with psoriasis, regarding diet and body weight

Are you living with psoriasis?

Would you be interested in helping us to develop a research project at Oxford University?

We will talk to people online and will reimburse:

· £30 for 60 minutes of your time

· Childcare costs

· Carer time

You can choose if you would prefer to join a small group conversation or talk to us 1:1.

We know that people are more likely to develop psoriasis, or for existing psoriasis to worsen, if they are also living with overweight or obesity. Research shows that a small amount of weight loss may improve psoriasis and is also likely to reduce the risk of related conditions, like type 2 diabetes, cardiovascular disease and metabolic syndrome. Doctors are encouraged to advise people with psoriasis and obesity to lose weight, but this does not happen regularly and is usually not very effective. We currently do not know the best way to support people living with psoriasis with weight management.

Our Oxford University research group is collaborating with King’s College London for this project. We want to work with people who are living with psoriasis to shape our research, learning about what matters most to you. We hope to chat about your experiences and opinions of weight change, diet and your skin. We will use these 

conversations to inform new dietary and lifestyle treatments for psoriasis, and to work out how best to test them in our research studies.

Please contact Dr. Sarah Morrow (Oxford University), sarah.morrow@phc.ox.ac.uk for more information regarding this project. We would be so glad to hear from you.

Chronic pain at work

Are you an employee with chronic pain or an employer working at a company with less than 250 employees? Researchers would like to hear from you!

Around 43% of people in the UK have chronic pain which can result in absenteeism and employment issues. Researchers lack the perspective of employees working from small - medium sized enterprises (SMEs) - companies with less than 250 employees. This is problematic given SMEs constitute 99.8% of all UK businesses. Glasgow Caledonian University are conducting interviews with employees from SMEs who have chronic pain and SMEs employers to understand their needs in relation to keeping employees at work. Your contribution will help us support people with chronic pain to remain at work.

Researchers are looking for people to take part in a brief questionnaire and a 1 hour online interview.

If you would like to take part, please email Ronald O'Kane at: ronald.okane@gcu.ac.uk

The HIPPOCRATES project

Called the HIPPOCRATES Prospective Observational Study (HPOS), the online study will monitor people with psoriasis over a three-year period to see who develops PsA. It will be completely remote with participants filling in questionnaires online and sending small fingerprick blood samples by prepaid post. Initially looking to recruit the volunteers from the UK, the ultimate goal is to recruit 25,000 people with psoriasis across 12 countries.

The study is part of wider research called The HIPPOCRATES project investigating psoriatic arthritis across Europe. It is a large consortium of over 25 research groups across Europe, led by Professor Oliver FitzGerald in Dublin which aims to answer 4 key research questions around psoriasis diagnosis, prediction, response to therapies, and prognosis on who will get joint damage.

If you would like to find out more about the project, or take part, you can find out more at the HPOS study website

Survey for people with psoriasis who are taking biologic treatment to help inform a study design

At the moment, doctors recommend that people continue regular biologic treatment for their psoriasis, even when their skin is well controlled (clear or nearly clear).

We know from clinical trials that some of these individuals may be able to stop treatment for a while, and then restart if / when the psoriasis begins to come back.

If people only take a drug when they need it this could reduce risks and burden to patients and give them more control, whilst also saving the NHS money.

Our research therefore aims to find out whether biologic treatments can be taken ‘as needed’ in routine care whilst still maintaining control of psoriasis.

Please help by filling out this survey:

https://forms.office.com/Pages/ResponsePage.aspx?id=FM9wg_MWFky4PHJAcWVDVldkFS5Tt5tDt6lgNXisraZUMFdGV1ZHUFpRSVhTNkdHSExaQ0I2SEdFVi4u

The Mediterranean diet and Time-Restricted Eating Dietary intervention for Psoriasis (METRED-P) Study- clinical study opportunity

The METRED-P study is a clinical trial evaluating the effects of different dietary patterns in individuals with psoriasis. This dietary intervention study will be the first to assess the effectiveness of these dietary patterns at modulating psoriasis severity.

The study consists of 3 clinic visits at the Metabolic Research Unit, Corridor A (4th Floor) in the Franklin−Wilkins Building, King’s College London, 150 Stamford Street, London, SE1 9NH. Virtual diet consultation sessions will be hosted by a Registered Associate Nutritionist who will consult participants to follow a Mediterranean style and/or time-restricted eating diet for 12 weeks.

Participants will record food and drink intakes in handwritten diet diaries, and complete confidential multiple-choice questionnaires about psoriasis. At the clinic visits, a Consultant Dermatologist will conduct a psoriasis examination and the Nutritionist will take body composition and clinic blood pressure measurements. A phlebotomist will collect a fasting blood sample (approximately 4.5 teaspoons). ​

To participate in the study, volunteers should be adults (18 years of age or older), have a diagnosis of plaque psoriasis​, have a body mass index between 20-40​ and should NOT be receiving phototherapy treatment for psoriasis​ currently or in the three months prior to participating in the study.

More information: https://www.dietandpsoriasisproject-apple.com/

Contact information: Sylvia Zanesco (Nutritionist): dietandpsoriasisproject@kcl.ac.uk

Opportunity for adolescent patients with psoriasis to take part in a trial comparing Risankizumab with Ustekinumab (OptIMMize-1)

***UPDATE - Please note that Parts 1, 2 and 3 of this study are now closed to recruitment. Recruitment for Part 4 of the study has not yet commenced – details will be announced in due course.***

This is an opportunity for 12-17 year old patients with moderate to severe plaque psoriasis. The trial, sponsored by the pharmaceutical company, AbbVie, compares the treatment efficacy and safety of Risankizumab (Skyrizi) vs Ustekinumab (Stelara), two biologic therapies. All participants are guaranteed active treatment, regardless of whether they have had systemic therapy before.

Recruitment criteria (list not exclusive):

  • Aged between 12 to < 18 years at the time of enrolment
  • Have had a diagnosis of chronic plaque psoriasis for at least 6 months
  • Have moderate to severe psoriasis, defined as ≥ 10% Body Surface Area (BSA) psoriasis involvement with a static Physician’s Global Assessment (sPGA) score of ≥ 3, or Psoriasis Area and Severity Index (PASI) ≥ 12

  • No history of:

  • Erythrodermic psoriasis, generalised or localised pustular psoriasis, medication-induced or medication exacerbated psoriasis, or new onset guttate psoriasis;
  • Active skin disease other than psoriasis that could interfere with the assessment of psoriasis;
  • Clinically significant drug or alcohol abuse within the last 6 months;
  • An allergic reaction or hypersensitivity to a biologic agent or its excipients;
  • A latex allergy;
  • An organ transplant that requires continued immunosuppression;
  • Any malignancy except for successfully treated non-melanoma skin cancer or localised carcinoma in situ of the cervix.

  • No evidence of:

  • Hepatitis B (HB) (hepatitis B virus [HBV]) or hepatitis C (hepatitis C virus [HCV]) infection;
  • Human immunodeficiency virus (HIV), defined as confirmed positive anti-HIV antibody (HIV Ab) test;
  • Genetic deficiency in IL-12/IL-23;

  • The following centres are open for recruitment into the study (please email the investigators directly):

  • West Ambulatory Care Hospital, Glasgow: Areti.Makrygeorgou@ggc.scot.nhs.uk
  • Frimley Park Hospital, Surrey: sara.sherif@nhs.net
  • Royal Devon and Exeter Hospital, Devon: naomi.goldstraw@nhs.net
  • Derriford Hospital, Plymouth: thurein.newin@nhs.net
  • Guy’s and St Thomas’ NHS Foundation Trust, London: please email Eva.Hilger@gstt.nhs.uk or call 07917217601

  • Dr Wedad Abdelrahman, Chief Investigator (wedad.abdelrahman@gstt.nhs.uk)
    Prof Carsten Flohr, Study Investigator (carsten.flohr@kcl.ac.uk)
    Consultant Paediatric Dermatologists

    St John’s Institute of Dermatology,
    Guy’s & St Thomas’ NHS Foundation Trust