Methotrexate dose

Posted Mon 8 Feb 2021 19.23 by JennyT

I start my medication of Methotrexate on Wednesday, and have been prescribed 15mg a week, which I thought was quite high?... I don’t have much psoriasis (tiny patch on my elbow)...... just wondering if anyone else had any thoughts on initial dose levels. Thanks I’m advance! (A little nervous about beginning it!! 😳).

Posted Mon 8 Feb 2021 20.01 by mike andrews

Hi. If you only have a tiny patch. I would ignore it and def not use medication. Mike

Posted Mon 8 Feb 2021 20.28 by JennyT

Thanks Mike, my Arthritis has been pretty bad though, it started last October, and just got my off diagnosis. I’ve been on naproxen, and had 2 cortisone injection to help with the inflammation. I have it in every joint I’m my body, so suffering somewhat. I’m only thankful the psoriasis is very minimal. I’m in no doubt that I need the drugs, just wondering if the dosage is normal. Thanks

Posted Mon 8 Feb 2021 21.06 by Steview
A P sufferer for over 30 years, through good and bad times.

Similar comment as Mike, if only a small patch I wasn't sure why thy would prescribe Mtx. As you also have PsA that is probably the main reason why you you have been prescribed it. I think you have to go with the dosage the specialist recommend and see how it goes. Is it equivelent injectable or tablet's? . It may give relie rom PA plus your small patch. Good luck.

Posted Fri 19 Feb 2021 23.13 by andrea
have had p for too many years

In response to Jenny T. I was surprised to see that you have been given such a high dose of methotrexate for a small patch. I had it over legs and body and lots of guttate patches and then I had to push to get it. I wouldn’t take it unless you had it far worse. I have now reduced mine from 17 mg to 2.5mg. It’s coming back but manageable with dovobet and my UVB light machine.

Posted Sat 20 Feb 2021 06.50 by JennyT

Hi Andrea, many thanks for your reply. I have been diagnosed with Psoriatic Arthritis, and suffer greatly with the arthritis side of things. I have carpel tunnel in both hands which effects my shoulders, and all my joints have been inflamed from the arthritis. I have been very fortunate ito have very little psoriasis, but my father had it pretty badly. I have since discovered that you don’t need to have the psoriasis all over in order to have the disease, hence my Rheumatologist putting on the drug . I’ve started my course on methotrexate and I’m delighted that I have very few side effects, just loss of appetite for a day or two. I’m really looking forward to the carpel tunnel disappearing, as it’s pretty annoying now! 😉

Posted Sat 20 Feb 2021 08.01 by andrea
have had p for too many years

Aw that’s a lot of pain management for you. I too have carpel tunnel in both hands. So long as I don’t do too many repetitive jobs like sewing by hand or turning pages of a book it’s not so painful. My mother had severe rheumatoid arthritis so I’ve seen how it can affect someone’s lives. Methotrexate made me so very tired so I took 34 mg of feroglobin iron tablets on alternative days or I wouldn’t have managed my two jobs. I feel so much better now I’ve reduced the methotrexate so just need to manage the much less psoriasis. I do hope this works for you Jenny 🤗

Posted Sat 20 Feb 2021 14.44 by fallon1983

Hello Jenny, sorry to hear of your psoriasis/artritis experience. Has the methotrexate worked? I am on hydroxycarbonmide tablets which cleared my skin (psorasis had spread on me over the years). However, I have one child. She developed psoriasis in April last year at 7 yrs old and I was looking for childhood treatments which is why I am asking about methotrexate as this was suggested for childhood treatment, obviously in smaller doses, I am trying to prepare my questions for my daughters next dermatologist appointment. Thank you, hope the pain has eased for you. Regards Fallon

Posted Sun 21 Feb 2021 07.06 by JennyT

Hi Fallon, your poor daughter, that must be really horrible for her. For me personally, I have only just started taking methotrexate, and so far had 2 doses over the last 2 weeks. I was really worried about all the potential side effects that I read about. Week 1, I just felt really tired and lost my appetite and felt a bit nauseous and a bit bunged up (Sorry, TMI 😆). This week, the tiredness was gone, and still had a loss of appetite on the day after taking it (I take them at 6 in the evening to try and sleep through the first part of the side effects, which seems to work well......) so 2 days after taking them ive felt pretty normal. I can’t tell you how pleased I am that I really haven’t had that badder experience, and am happy to carry on. It will be up to 3 months before I. Notice any improvements, so my carpel tunnel hasn’t gone, but I’m in it for the long haul, so fingers crossed (no pun intended 😆 🤞) That I see an improvement. As for Your daughter, we all react differently, and I would hope she, like me, would have limited side effects, but obviously I can’t say for sure, Take care, and once again good luck. 🤞😉

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