Dupixent (Dupilumab) treatment

Posted Thu 29 Apr 2021 17.48 by Vicky

Hi, has anyone tried the Dupixent (Dupilumab) treatment at all. It is a biologic treatment that you inject yourself (like an epi-pen) every 2 weeks. I just wondered how good it was before I ask my consultant in a few months time, & can it be used long term, as I have read about it & it sounds amazing. Thank you!

Posted Thu 29 Apr 2021 17.53 by scarletsmummy

i have never heard of it being used for Psoriasis as its a treatment used for eczema

Posted Thu 29 Apr 2021 18.03 by lizziep (edited Thu 29 Apr 2021 18.04 by lizziep)

I agree with scareletmummy - I thought it` was only used for eczema - I googled it and it makes no mention of psoriasis.``

Posted Fri 30 Apr 2021 03.40 by Yacht

A quick look at the dupilumab page on Wikipedia today makes absolutely zero mention of psoriasis. It blocks IL-4 and IL-13 signals, neither of which is used currently for psoriasis. The most effective biologics for psoriasis, right now, appear to be risankizumab, guselkumab and ixekizumab.

Posted Fri 30 Apr 2021 14.59 by Vicky

Thank you everyone for the info, interesting & very helpful!

Posted Sat 1 May 2021 19.29 by Yacht

Etanercept has very low efficacy. Studies suggest just a 20% chance of getting 90% clearance (PASI 90). Risankizumab, guselkumab and ixekizumab have around 70-75% chance of PASI 90.

Posted Sun 2 May 2021 15.45 by Vicky

Thank you all for the info!

Posted Thu 17 Jul 2025 09.17 by mash61 (edited Thu 17 Jul 2025 09.17 by mash61)

Before starting, I had to fill out the Dupixent enrollment form https://startforms.health/dupixent-enrollment-form/ , which my dermatologist gave me. That helps with getting coverage and support programs if needed. It’s definitely worth discussing with your consultant when the time comes. For me, it’s been life-changing and I’d 100% recommend looking into it if you're eligible.

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