Amgevita has stopped working
Posted Mon 13 Oct 2025 22.05 by Ld1609
Hello, I wonder if anyone else has found Amgevita has stopped working? I have been injecting for my severe pso for 2yrs and in the last 6 weeks i have found new patches of pso developing, having had clear skin for 20ish months. Of course i feel absolutely petrified and full of anxiety because im worried my derm will give me the routine “lets take you off Amgevita and see how your skin responds”! When i know full well how my skin will respond, it will go into full flare up mode and i will be covered in pso again and in pain and discomfort. I feel really anxious and worried about it! Has anyone else found that Amgevita has stopped working for them? And did you find that the next step was to increase the dosage and did that help? Any help much appreciated, Leanne
Yes, I was on Humira initally and was changed to biosimilar. It had amazing relief for my skin and joints for nearly 5 years. I developed antibodies. My prescription changed to another TNF alpha blocker Benepali (Etenercept) by my rheumatologist. On it for couple of years- joints inflammation under control but skin got worse,resistant to photothreapy and topical treaments. Started MTX 2 weeks ago, my dermatologist in liaison with Rheumatologist finally decided to try another biologiC -IL17 BLOCKER bimekuzumab - awaiting for its approval
Living in hope that the new treatment will work once it is started
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