The 'Top Ten' list, agreed upon by patients, carers and clinicians, marks the culmination of the psoriasis Priority Setting Partnership (PSP)
We are delighted to announce the Top
Ten Psoriasis Research Priorities, agreed upon by people who are living with psoriasis, carers and
healthcare professionals. This 'Top Ten' list – the culmination of the psoriasis Priority Setting Partnership (PSP)
- will be considered by research funders to ensure future psoriasis research
focuses on the areas that matter most to the 1.8 million people in the UK who
live with the condition, and those involved in its care and treatment.
The project followed the James Lind Alliance’s Priority
Setting Partnership method, and began with an open call for psoriasis
stakeholders to submit the questions that they wanted answering about the condition
and its treatments. Over two thousand questions were received from people
living with the condition, their families, GPs, Dermatologists, Nurses and others.
These questions were refined through a rigorous and collaborative process,
including a second round of voting and a stakeholder workshop day to agree on
the 'Top Ten'.
The Top Ten Psoriasis Research Priorities are:
1. Do lifestyle
factors such as diet, dietary supplements, alcohol, smoking, weight loss and
exercise play a part in treating psoriasis?
treating psoriasis early (or proactively) reduce the severity of the disease,
make it more likely to go into remission, or stop other health conditions
factors predict how well psoriasis will respond to a treatment?
is the best way to treat the symptoms of psoriasis: itching, burning, redness,
scaling and flaking?
well do psychological and educational
interventions work for adults and children with
treating psoriasis help improve other health conditions, such as psoriatic
arthritis, cardiovascular disease, metabolic syndrome and stress?
7. Why do
psoriasis treatments stop working well against psoriasis and when they stop
working well, what’s the best way to regain control of the disease?
what extent is psoriasis caused by a person’s genes or other factors, such as
stress, gut health, water quality, or change in the weather / temperature?
9. Is a person with psoriasis more likely to
develop other health conditions (either as a consequence of psoriasis or due to
the effect of treatments for psoriasis)? If so, which ones?
the best way to treat sudden flare ups of psoriasis?
Helen McAteer, Chief Executive of the Psoriasis Association,
comments, “Traditionally, academic researchers and commercial interests have dominated
the research agenda in psoriasis. The Priority Setting Partnership offered an
opportunity for people living with psoriasis, their family members, and the
healthcare professionals treating them to have their say on the future of
psoriasis research. We can be confident that the Top Ten priorities we now have
before us reflect the real interests of people affected by psoriasis, and they
will ensure that work is carried out in these areas. ”
Dr Helen Young, Lead for the psoriasis Priority Setting Partnership,
comments, “Our entire endeavour has had both a patient and health-care
The robustness of the Psoriasis PSP has been due to the rigour of the PSP
Steering Group who have had oversight of the project in addition to the
collaboration with individuals (both patients, carers and healthcare
professionals) and our partnership with The Psoriasis Association, UK
Dermatology Clinical Trials Network, the British Association of Dermatologists,
the British Dermatological Nursing Group, the Primary Care Dermatology Society,
and the International Psoriasis Council. We are enormously grateful for the
support of the James Lind Alliance who have facilitated the Psoriasis PSP.”