Dexamethasone is a steroid. It has been used in the
past for psoriasis, but it is not a good long-term treatment for
psoriasis as it can lead to other complications such as weight gain,
indigestion, sleep problems, mood changes, glaucoma, osteoporosis, high blood
pressure and diabetes.
We also see a ‘rebound phenomenon’ with steroids
after they are stopped or withdrawn in psoriasis. Essentially this means that
your psoriasis can worsen once steroids are suddenly stopped. This is why we
only tend to use topical steroids on the skin in psoriasis where this
phenomenon is not such an issue.
Dexamethasone is sometimes used in a specific phase
of illness with COVID-19. It is not used in the early phases of infection where
the virus is thought to be replicating. Instead, it is used in the later phases
of the illness in severely unwell patients who have developed a
hyperinflammatory syndrome to the virus.