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22 March 2018

New Biologic Treatment Approved for Psoriasis in the UK

The National Institute for Health and Care Excellence (NICE) has  published its Final Guidance on the use of brodalumab (Kyntheum) for severe psoriasis in England and Wales.

Brodalumab (Kyntheum) is recommended to treat severe psoriasis, where people have not had adequate results from conventional systemic treatments, or cannot take them.

Brodalumab blocks the activity of interleukin 17A (IL-17A), a chemical ’messenger’ in the immune system that signals other cells to cause inflammation. In people with psoriasis the immune system is overactive and creates too much inflammation, which leads to the development of psoriasis symptoms. By blocking IL-17A, Kyntheum aims to prevent some of that inflammation from occurring, leading to an improvement in psoriasis for some people who take it. Other biologic medications that block the activity of IL-17A, called Cosentyx (secukinumab) and Taltz (ixekizumab) are currently available for people with severe psoriasis.

We will be publishing more information on brodalumab (Kyntheum) for psoriasis soon. In the meantime, please get in touch with us if you have any questions.

The Psoriasis Association is the UK's leading national charity and membership organisation for people affected by psoriasis – patients, families, carers and health professionals Read More >

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The Psoriasis Association Dick Coles House 2 Queensbridge Northampton NN4 7BF


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